Clinical efficacy and mechanism of acupuncture for Parkinson's disease
10.3760/cma.j.cn115398-20211123-00286
- VernacularTitle:针刺治疗帕金森病的临床疗效与机制研究进展
- Author:
Jingyi LIU
1
;
Zichen ZHANG
;
Yadan ZHAO
;
Haixia CHEN
;
Yinjie CUI
;
Zhifang XU
Author Information
1. 天津中医药大学实验针灸研究中心2020级硕士研究生，天津 301617
- Keywords:
Acupuncture therapy (TCM);
Parkinson disease;
Dopamine;
α-synuclein;
Review
- From:
International Journal of Traditional Chinese Medicine
2022;44(11):1323-1327
- CountryChina
- Language:Chinese
-
Abstract:
Acupuncture can improve the motor and non-motor symptoms of Parkinson's disease, and the effect of acupuncture combined with drug therapy is better than that of drug therapy alone. The possible mechanism includes inhibiting α-synuclein aggregation, oxidative stress, and neuroinflammation, inhibiting the apoptosis of dopaminergic neurons, and achieving a neuroprotective effect. The points mainly selected for Acupuncture treatment for this disease are Zusanli (ST 36), Yanglingquan (GB 34), Taichong (LR 3), Xuehai (SP 10), and other points. Early use of acupuncture and acupuncture combined with medical treatment strategy is worthy of clinical application.
