Research progress on the pharmacological effects and pharmacokinetics of linarin
10.3760/cma.j.cn115398-20201220-00212
- VernacularTitle:蒙花苷药理作用及药代动力学研究进展
- Author:
Zhifeng LIU
1
;
Peiyan LI
;
Yuansheng TAN
;
Kelin YANG
Author Information
1. 佛山科学技术学院2019级硕士研究生,佛山 528231
- Keywords:
Buddleoside;
Pharmacologic actions;
Pharmacokinetics;
Pharmacology (TCD);
Active constituent;
Review
- From:
International Journal of Traditional Chinese Medicine
2022;44(6):716-720
- CountryChina
- Language:Chinese
-
Abstract:
Linarin, as a natural coumponent belongs to flavonoid glycoside, is widely existed in herbal plants such as chrysanthemum indicum and Mongolian flower, which has a variety of pharmacological effects, such as anti-inflammation, anti-cancer, liver protection, analgesia, antipyretic, anti-oxidation, anti-apoptosis, sedation and sleep, neuroprotection, preventing and treating hypertension, treatingdiabetes, preventing and treating osteoporosis, whitening, skin care and sunscreen. It is difficult to dissolve in water and has poor oral efficacy, but when combined with different substances or combined (forming phospholipid complex), its bioavailability can be improved, so as to improve its pharmacological efficacy.