Research progress on the malignant transformation of oral submucosal fibrosis
10.3760/cma.j.cn371439-20220609-00120
- VernacularTitle:口腔黏膜下纤维化恶变的研究进展
- Author:
Changqun ZHOU
1
;
Xiaoyan GUAN
;
Jianguo LIU
;
Chaoyi YUE
;
Chengcheng LIAO
Author Information
1. 遵义医科大学附属口腔医院正畸科二组，遵义 563000
- Keywords:
Oral submucous fibrosis;
Oral neoplasms;
Malignant change
- From:
Journal of International Oncology
2022;49(10):608-611
- CountryChina
- Language:Chinese
-
Abstract:
Oral submucous fibrosis (OSF) can cause various oral dysfunctions in patients and can turn into oral cancer. The causes and processes of OSF malignant transformation involve betel nut chewing, vascular atrophy, tissue hypoxia, cell cycle changes, aging, autophagy, and changes in cancer/cancer suppressor genes and microRNAs. It is of great significance to study the causes and process of OSF malignant transformation for the treatment and prevention of OSF malignant transformation.
