Research progress of radiation recall pneumonitis caused by immune checkpoint inhibitors

VernacularTitle:免疫检查点抑制剂引发放射唤醒性肺炎的研究进展
Author: Jie ZHANG ¹ ; Meizhuo WEI ; Ling ZHAO ; Shanyong YI
Author Information

1. 新乡医学院研究生院，新乡　453003
Keywords: Immune checkpoint inhibitors; Immunotherapy; Radiotherapy; Pneumonia; Radiation pneumonitis
From: Journal of International Oncology 2022;49(10):577-580
CountryChina
Language:Chinese
Abstract: At present, tumor therapy has entered the era of immunotherapy. However, in recent years, it has been found that the application of immune checkpoint inhibitors after chest radiotherapy can not only play a synergistic anti-tumor effect, but also cause radiation recall pneumonitis (RRP). RRP is a rare immune-related adverse reaction, which even leads to death in severe cases. It is of great significance to study the mechanisms and influencing factors of RRP caused by immune checkpoint inhibitors for strengthening the cognitive management of RRP and reducing the risk of RRP.