CRISPR/Cas9 genome editing technology and its applications in tumor therapy
10.3760/cma.j.cn371439-20220408-00106
- VernacularTitle:基于CRISPR/Cas9的基因编辑技术及其在肿瘤治疗中的应用
- Author:
Ziyue ZHANG
1
;
Sihao ZHENG
;
Yanjun GAO
;
Yi YAO
;
Qibin SONG
Author Information
1. 武汉大学人民医院肿瘤中心，武汉 430060
- Keywords:
Neoplasms;
Gene editing;
Immunotherapy;
Oncolytic virotherapy;
CRISPR/Cas9 genome editing technique
- From:
Journal of International Oncology
2022;49(9):546-549
- CountryChina
- Language:Chinese
-
Abstract:
Gene editing technology CRISPR/Cas9 and its derivative editing technologies including base editor and prime editor can precisely edit the target genome sequences, having been widely used in tumor therapy and achieved remarkable clinical results in tumor immunotherapy, human papilloma virus infection treatment and oncolytic virotherapy, providing a new means for tumor therapy.
