Research status of glioblastoma-associated microglia
10.3760/cma.j.cn371439-20220429-00080
- VernacularTitle:胶质母细胞瘤相关小胶质细胞研究现状
- Author:
Wenjing FEI
1
;
Wenbao WANG
;
Huanhuan XIE
;
Jing YAN
;
Mi YANG
Author Information
1. 南京医科大学鼓楼临床医学院肿瘤中心，南京 210008
- Keywords:
Brain neoplasms;
Immunomodulation
- From:
Journal of International Oncology
2022;49(7):420-424
- CountryChina
- Language:Chinese
-
Abstract:
Microglia differ from macrophages with unique origin and role. In glioblastoma, microglia plays an important role in regulating tumor immune status, promoting tumor angiogenesis, destroying the blood-brain barrier, and reducing the sensitivity of treatment. Therefore, the combination of microglial therapy in the radiotherapy, chemotherapy and immunotherapy of glioblastoma has also become a clinically promising treatment.
