Research progress of circRNA in breast cancer drug resistance
10.3760/cma.j.cn115396-20220627-00210
- VernacularTitle:circRNA在乳腺癌耐药中的研究进展
- Author:
Xingyu CHEN
1
;
Ru YI
;
Deyuan FU
;
Fenglin CAI
Author Information
1. 大连医科大学，大连 116044
- Keywords:
Breast neoplasms;
Molecular biology;
RNA, circular;
Drug resistance
- From:
International Journal of Surgery
2022;49(10):713-717
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is the most common cancer among women worldwide, and it seriously threatens women′s life and health. circular RNA (circRNA) play a key role in the development and drug resistance of various cancers, including breast cancer. circRNA is an endogenous RNA molecule with a single-stranded closed structure, which has unique biological characteristics and function, and is a current research hotspot. This article will review circRNA as potential biomarkers to predict breast cancer drug resistance and therapeutic targets.
