Progress of drug-loaded β-tricalcium phosphate in the treatment of bone defects
10.3760/cma.j.cn115396-20220425-00135
- VernacularTitle:β－磷酸三钙联合载药治疗骨缺损的研究进展
- Author:
Yujie JIN
1
;
Xiao YU
;
Xiaoqiang ZHOU
;
Jingyu ZHANG
;
Renjie XU
;
Xiangxin ZHANG
;
Guangxiang CHEN
Author Information
1. 南京医科大学姑苏学院 南京医科大学附属苏州医院 苏州市立医院关节外科，苏州 215000
- Keywords:
β-tricalcium phosphate;
Bone defect;
Bone regeneration;
Bone substitutes;
Drug delivery systems
- From:
International Journal of Surgery
2022;49(7):473-479
- CountryChina
- Language:Chinese
-
Abstract:
Bone defects caused by trauma, infection, tumor and other factors is a thorny problem in orthopedic clinic, and promoting bone repair and regeneration is the key and difficult point of treatment. In addition to autologous bone grafting, artificial bone materials are often used for large bone defects. β-tricalcium phosphate has good biocompatibility, bone conduction and bone induction properties, and has been studied deeply because of its excellent drug delivery performance and has shown broad application prospects. In this paper, the author will summarize the research progress of β-tricalcium phosphate composites loaded with different drugs in the treatment of bone defects caused by trauma, infection and tumor.
