Corneal confocal microscopy and its application in ischemic cerebrovascular disease
10.3760/cma.j.issn.1673-4165.2022.08.008
- VernacularTitle:角膜共聚焦显微镜及其在缺血性脑血管病中的应用
- Author:
Jihong LIU
1
;
Yingxiao JI
;
Min CHEN
;
Rui ZHAI
;
Zhipeng CAI
;
Litao LI
Author Information
1. 华北理工大学研究生院，唐山 063210
- Keywords:
Cerebrovascular accident;
Brain ischemia;
Microscopy, confocal;
Cornea;
Nerve fibers
- From:
International Journal of Cerebrovascular Diseases
2022;30(8):605-610
- CountryChina
- Language:Chinese
-
Abstract:
Corneal confocal microscopy (CCM) is an in vivo corneal imaging technique, which can directly quantify corneal nerve fibers in real time. It has the characteristics of non-invasive, objective and high sensitivity. CCM can not only be used for the diagnosis and treatment evaluation of corneal diseases, but also plays an important role in the diagnosis and prognosis evaluation of some peripheral and central nervous system diseases, such as diabetes peripheral neuropathy and Parkinson's disease. In addition, the changes of corneal nerve fibers can indirectly reflect the severity of ischemic cerebrovascular disease, and it is expected to become a noninvasive bioimaging marker of ischemic cerebrovascular disease. This article reviews CCM and its application in ischemic cerebrovascular disease, in order to provide better means for early diagnosis and prognosis evaluation of ischemic cerebrovascular disease.
