Damage mechanism of neurovascular unit in cerebral small vessel disease
10.3760/cma.j.issn.1673-4165.2022.07.006
- VernacularTitle:脑小血管病的神经血管单元受损机制
- Author:
Shujie LI
1
;
Xiaoxiao LI
;
Yongsheng HAN
Author Information
1. 安徽中医药大学研究生院，合肥 230012
- Keywords:
Cerebral small vessel diseases;
Cerebrovascular circulation;
Blood-brain barrier
- From:
International Journal of Cerebrovascular Diseases
2022;30(7):513-518
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral small vessel disease (CSVD) is a common and slowly progressive cerebrovascular disease. Its pathological mechanism involves vascular endothelial dysfunction, blood-brain barrier destruction, neuronal apoptosis, glial cell activation, and inflammatory reaction. Neurovascular unit is the basic unit of brain structure and function, and its pathological changes are closely associated with many cerebrovascular diseases. At present, the damage mechanism of neurovascular unit in CSVD has been paid more and more attention. This article reviews the damage mechanism of neurovascular unit in CSVD.
