Bone marrow mesenchymal stem cell-derived exosomes in the treatment of ischemic stroke

VernacularTitle:骨髓间充质干细胞外泌体治疗缺血性卒中
Author: Yang JIN ¹ ; Yichen CAI ; Yunsha ZHANG ; Shixin XU
Author Information

1. 天津中医药大学中西医结合学院，天津　301617
Keywords: Stroke; Brain ischemia; Bone marrow cells; Mesenchymal stem cells; Exosomes
From: International Journal of Cerebrovascular Diseases 2022;30(5):369-374
CountryChina
Language:Chinese
Abstract: Stem cell transplantation has great potential in the treatment of ischemic stroke, and bone marrow mesenchymal stem cells (BMSCs) are the most widely studied. Studies have shown that BMSCs mainly perform their functions in a paracrine manner, and the exosomes released by BMSCs show biological activities similar to BMSCs. As a cell-free therapy, BMSCs exosomes have made a lot of progress in the field of ischemic stroke. This article reviews the research progress of BMSCs-derived exosomes in the treatment of ischemic stroke.