Protective effect of fibroblast growth factor 21 on ischemic stroke
10.3760/cma.j.issn.1673-4165.2022.05.009
- VernacularTitle:成纤维细胞生长因子21对缺血性卒中的保护作用
- Author:
Jingyu ZHAO
1
;
Xiaoyi CHEN
;
Ya ZHANG
;
Hui ZHANG
;
Peiyuan LYU
;
Yanhong DONG
Author Information
1. 华北理工大学研究生学院，唐山 063000
- Keywords:
Stroke;
Brain ischemia;
Fibroblast growth factors;
Cognition disorders;
Neuroprotective agents;
Blood-brain barrier;
Inflammation;
Oxidative stress;
Microglia
- From:
International Journal of Cerebrovascular Diseases
2022;30(5):365-368
- CountryChina
- Language:Chinese
-
Abstract:
As a multifunctional signal molecule, fibroblast growth factor 21 (FGF21) has been proved to have a variety of biological effects, including anti-inflammatory, antioxidant stress, and neuroprotection. This article reviews the latest research progress on the protective effect of FGF21 in ischemic stroke and its relationship with cognitive impairment.
