Remnant cholesterol and ischemic stroke
10.3760/cma.j.issn.1673-4165.2022.04.007
- VernacularTitle:残余胆固醇与缺血性卒中
- Author:
Xin ZHAO
1
;
Xin JIANG
;
Pei CUI
;
Peiyuan LYU
;
Yanhong DONG
Author Information
1. 华北理工大学研究生院,唐山 063000
- Keywords:
Stroke;
Cerebral ischemia;
Cholesterol;
Lipoproteins;
Triglycerides;
Atherosclerosis;
Risk factors
- From:
International Journal of Cerebrovascular Diseases
2022;30(4):280-284
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis (AS) is one of the pathological bases of ischemic stroke. AS caused by elevated low-density lipoprotein cholesterol levels is the main causative factor. However, recent studies have found that the traditional blood lipid indicators can not fully reflect the risk of stroke in high-risk populations. Non-traditional blood lipid parameters are developed from traditional blood lipid parameters, including remnant cholesterol (RC), non-high density lipoprotein cholesterol and a variety of blood lipid ratios, which may play a role in the prevention and treatment of cerebrovascular diseases. Among them, RC is increasingly recognized as a biomarker driving the residual risk of AS. It has been confirmed that RC is closely associated with the risk of cerebrovascular disease in the primary and secondary prevention studies of stroke.