Advances in the malnutrition of pediatric chronic cholestatic disease
10.3760/cma.j.issn.1673-4408.2022.11.010
- VernacularTitle:儿童慢性胆汁淤积致营养不良研究进展
- Author:
Zhi YANG
1
;
Biquan CHEN
Author Information
1. 安徽省儿童医院感染科，合肥 230051
- Keywords:
Children;
Cholestasis;
Chronic liver disease;
Malnutrition
- From:
International Journal of Pediatrics
2022;49(11):767-772
- CountryChina
- Language:Chinese
-
Abstract:
Despite recent advances in pediatric chronic cholestatic diseases, the causes and effective therapies remain elusive, and many patients progress to liver failure and need liver transplantation.Malnutrition is a common complication in these patients and is a well-recognized, tremendous challenge for the clinician.The malnutrition and failure to thrive are associated with increased risks of morbidity and mortality, and they also affect the outcomes of liver transplantation, including long-term survival.Malnutrition in children with chronic cholestatic disease is multifactorial and with multiple potential nutritional deficiencies.Supplemental feeding, including medium-chain triglycerides, essential fatty acids, branched-chain amino acids.In order to improve the life expectancy and quality of life of children with chronic liver disease, this paper reviews ways to address the nutritional needs for specific cause of malnutrition in children.
