Advances in diagnosis and treatment of multisystem inflammatory syndrome in children
10.3760/cma.j.issn.1673-4408.2022.11.002
- VernacularTitle:儿童多系统炎症综合征诊治进展
- Author:
Jiazhuo TANG
1
;
Miao LIU
;
Zhangwu LIANG
;
Yi JIANG
Author Information
1. 武汉大学人民医院儿科 430060
- Keywords:
Children;
Multisystem inflammatory syndrome in children;
Severe acute respiratory syndrome coronavirus 2;
Coronavirus disease 2019;
Kawasaki disease
- From:
International Journal of Pediatrics
2022;49(11):728-733
- CountryChina
- Language:Chinese
-
Abstract:
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection may lead to multisystem inflammatory syndrome in children(MIS-C). MIS-C mostly occurs in older children and adolescents who have laboratory or epidemiological evidence of SARS-CoV-2 infection.The clinical manifestations include persistent fever, hypotension, elevated inflammation markers, and symptoms of multiple organ involvement, which is similar to Kawasaki disease.Once the disease occurs, it can progress rapidly and worsen in a short time, and most children require intensive care admission.Although the overall prognosis is good, some patients have adverse results such as death.We should strengthen the monitoring and management of suspected children and improve the level of diagnosis and treatment of the disease.