Fluid overload in critically ill children and advances in its treatment
10.3760/cma.j.issn.1673-4408.2022.11.001
- VernacularTitle:危重患儿液体超载及其治疗研究进展
- Author:
Huiying HE
1
;
Jing LI
;
Lan HU
Author Information
1. 重庆医科大学附属儿童医院重症医学科 国家儿童健康与疾病临床医学研究中心 儿童发育疾病研究教育部重点实验室 儿童发育重大疾病国家国际科技合作基地 儿科学重庆市重点实验室 400014
- Keywords:
Children;
Fluid overload;
Diuretics;
Ultrafiltration;
Net ultrafiltration intensity
- From:
International Journal of Pediatrics
2022;49(11):723-727
- CountryChina
- Language:Chinese
-
Abstract:
Fluid overload(FO)is significantly associated with survival in critically ill children.Excessive fluid accumulation in the body causes tissue oedema, which may lead to heart failure, acute kidney injury(AKI)and acute pulmonary oedema, affecting length of hospital stay, readmission rates and prognosis.According to the cause of the FO, the main treatments are fluid restriction, diuretics, and ultrafiltration.Diuretics are often used clinically to treat patients with FO.International guidelines recommend ultrafiltration to remove excess water when diuretic therapy is not effective or when diuretic resistance occurs, or when life-threatening complications arise.However, there is no conclusion on the setting for the net ultrafiltration intensity in ultrafiltration, particularly in critically ill children.With the development of ultrafiltration technology, the application of ultrafiltration in the treatment of FO patients will be further carried out.This article provides a review of the FO and its treatment in critically ill children.
