Advance in tic disorder related genes in children
10.3760/cma.j.issn.1673-4408.2022.06.008
- VernacularTitle:儿童抽动障碍相关基因的研究进展
- Author:
Yingying CHAI
1
;
Wenxin LIN
;
Guo ZHENG
;
Yanjun HUANG
Author Information
1. 南京医科大学附属儿童医院神经内科 210000
- Keywords:
Tic disorders;
Genetic;
Genes
- From:
International Journal of Pediatrics
2022;49(6):389-392
- CountryChina
- Language:Chinese
-
Abstract:
Tic disorders(TD), a complex chronic neuropsychiatric disorder characterized by rapid, involuntary, non rhythmic, single or multiple muscle movements or vocal twitches, usually occurs in children aged from 2 to 15 years.TD has various clinical manifestations, which are usually related to various psychopathology or behavioral comorbidities, including attention deficit hyperactivity disorder, anxiety, depression and obsessive-compulsive disorder.The etiology and pathogenesis of TD are still not completely clear.Immune, genetic, neurobiochemical and environmental factors are generally recognized as factors related to the pathogenesis of TD.In recent years, the research on TD and genetic factors has gradually increased, but so far there is no clear conclusion on the pathogenic genes of TD.This paper only discusses the genes related to TD.