Historical Evolution and Modern Research Progress of Processing of Notoginseng Radix et Rhizoma
10.13422/j.cnki.syfjx.20230247
- VernacularTitle:三七炮制的历史沿革及现代研究进展
- Author:
Yazhen GAO
1
;
Junbo ZOU
2
;
Ming YANG
1
;
Fengqin LI
1
;
Xing LEI
1
;
Weijie WEN
1
;
Haizhen LIU
1
;
Hao LU
1
;
Yan ZHANG
1
;
Fang WANG
1
Author Information
1. Jiangxi University of Chinese Medicine,Nanchang 330004,China
2. College of Pharmacy,Shaanxi University of Chinese Medicine,Xianyang 712046,China
- Publication Type:Journal Article
- Keywords:
Notoginseng Radix et Rhizoma;
different uses of raw and processed products;
historical evolution;
processing method;
Chinese Pharmacopoeia;
material basis;
mechanism of action
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2023;29(4):212-220
- CountryChina
- Language:Chinese
-
Abstract:
By reviewing the relevant literature of ancient herbal works and modern codices, this paper sorted out the historical evolution and developmental venation of processing of Notoginseng Radix et Rhizoma. On this basis, the modern research of processed products of Notoginseng Radix et Rhizoma was used as the breakthrough point to analyze the literature in terms of processing technology, chemical composition changes and changes in pharmacological effects before and after processing. According to the research status of processing of Notoginseng Radix et Rhizoma, some existing problems were analyzed in this paper, such as not many ancient processing methods used in modern time, lack of standardized research on processing technology. And saponins, polysaccharides, amino acids, flavonoids and other chemical components in Notoginseng Radix et Rhizoma may change to different degrees before and after processing, which was the main reason for the difference of efficacy before and after processing. However, the current research on the pharmacological effects of Notoginseng Radix et Rhizoma mainly focuses on raw products, resulting in a lack of in-depth research on the transformation mechanism of Notoginseng Radix et Rhizoma in processing difference, and the scientific connotation of "Shengxiao Shubu" has not been clearly elaborated, which is not conducive to the standardized clinical use of drugs. Therefore, it is necessary to further analyze the material basis of Notoginseng Radix et Rhizoma and its processed products, and to explore the change rule of chemical components before and after processing and its correlation with pharmacodynamic activity, so as to clarify the processing mechanism for providing scientific basis for its standardized processing, quality control and clinical rational use.