Case of Langerhans Cell Histiocytosis That Mimics Meningioma in CT and MRI.
10.3340/jkns.2016.59.2.165
- Author:
Ming ZHU
1
;
Bing Bing YU
;
Ji Liang ZHAI
;
Gang SUN
Author Information
1. Department of Medical Imaging, Jinan Military General Hospital, Jinan, China. cjr.sungang@vip.163.com
- Publication Type:Case Report
- Keywords:
CT;
MRI;
Meningioma;
Langerhans cell histiocytosis
- MeSH:
Adolescent;
Brain;
Diagnosis;
Diagnosis, Differential;
Dura Mater;
Female;
Histiocytosis, Langerhans-Cell*;
Humans;
Langerhans Cells;
Magnetic Resonance Imaging*;
Meningioma*;
Pathology;
Skull;
Tail
- From:Journal of Korean Neurosurgical Society
2016;59(2):165-167
- CountryRepublic of Korea
- Language:English
-
Abstract:
Langerhans cell histiocytosis (LCH) is a rare disorder histologically characterized by the proliferation of Langerhans cells. Here we present the case of a 13-year-old girl with LCH wherein CT and MRI results led us to an initially incorrect diagnosis of meningioma. The diagnosis was corrected to LCH based on pathology findings. An intracranial mass was found mainly in the dura mater, with thickening of the surrounding dura. It appeared to be growing downward from the calvaria, pressing on underlying brain tissue, and had infiltrated the inner skull, causing a bone defect. The lesion was calcified with the typical dural tail sign. The dural origin of the lesion was verified upon surgical dissection. There are no previous reports in the literature describing LCH of dural origin presenting in young patients with typical dural tail signs and meningioma-like imaging findings. The current case report underscores the need for thorough histological and immunocytochemical examinations in LCH differential diagnosis.
