Clinical effect of compound phellodendron gargle with total glucosides of paeony capsule in the treatment of erosive oral lichen planus
10.12206/j.issn.2097-2024.202208052
- VernacularTitle:复方黄柏液联合白芍总苷胶囊治疗糜烂型口腔扁平苔藓的短期临床疗效观察
- Author:
Ruihan WU
1
;
Yanhong MA
1
Author Information
1. Department of Stomatology, Xuzhou Central Hospital, Xuzhou 221009, China.
- Keywords:
compound phellodendron gargle;
oral lichen planus;
total glucosides of paeony;
erosive
- From:
Journal of Pharmaceutical Practice
2023;41(1):56-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the short-term clinical effect of compound phellodendron gargle combined with the total glucosides of paeony (TGP) in the treatment of erosive oral lichen planus (OLP). Methods 62 patients were divided into observation group and control group through a designed parallel randomized controlled study. All the patients used the total glucosides of paeony capsule , the patients in the observation group also used the compound phellodendron gargle. The pain condition, the healing condition of face, and the treatment effective in both group were evaluated through physical signs and VAS scores evaluations by SPSS 22.0, which could further evaluate the short-term clinical efficacy of compound phellodendron. Results After 30 days, the scores of VAS and physical signs of each group are much better than before. And the scores of VAS and treatment effective of observation group were significantly better than those of the other control groups (P<0.05). Conclusion The application of phellodendron gargle with total glucosides of paeony capsule could improve the treatment effect of OLP patients and reduce the oral pain , which could be used widely in clinical practice.
