Analysis of medication rules of TCM for perimenopausal syndrome based on literature mining
10.12206/j.issn.2097-2024.202203034
- VernacularTitle:基于数据挖掘对中医药治疗围绝经期综合征用药规律的研究
- Author:
Min GAO
1
;
Yingbo YANG
2
,
3
;
Li LIN
2
,
3
;
Lingxuan YING
4
;
Lianna SUN
4
;
Wei XIAO
2
,
3
Author Information
1. Chinese Medicine Research Institute, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
2. Chinese Medicine Research Institute, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
3. Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
4. College of Traditional Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
- Keywords:
menopausal syndromes;
TCM;
data mining;
medication rule
- From:
Journal of Pharmaceutical Practice
2023;41(1):31-35
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the rules of Traditional Chinese Medicine in the treatment of perimenopausal syndrome (PMS) and provide a theoretical basis for the clinical treatment of PMS. Methods The literature related to PMS were collected from China Knowledge Network (CNKI), Wanfang database and Weipu database in the past 20 years, the herbal compound prescriptions for the treatment of PMS were screened and a relevant database were established and analyzed by SPSS. Results The relevant literatures contains 184 Chinese medicine prescriptions/proprietary Chinese medicines, 122 flavors of traditional Chinese medicines, and the drug categories were mainly tonic drugs, antipyretic drugs, astringent drugs, and tranquilizers. The core single-flavor Chinese medicines were Baishao(Radix Paeoniae Alba), Shudihuang(Rehmannia glutinosa ), Danggui(Radix Angelicae Sinensis), Fuling (Indian Buead). The property and flavor covered sweet, bitter, cold, etc.; and the channel tropism belonged to the liver, kidneys, heart, lungs, spleen and meridians. The cluster analysis of high-frequency Traditional Chinese Medicine obtained two main combinations. Conclusion TCM treatment of PMS focused on replenishing qi, soothing the liver, nourishing the kidneys, nourishing blood and calming the heart, and then according to clinical compatibility with drugs such as soothing the nerves, clearing heat and removing dampness; most of its clinical treatment were Xiaoyaosan, Liuwei Dihuang pills, and Zhibo Rehmanniae decoction and other prescriptions which were added and subtracted.
