Research progress on deep hypothermic circulatory arrest in rat model
- VernacularTitle:深低温停循环大鼠模型研究进展
- Author:
Weidong YAN
1
;
Bingyang JI
1
Author Information
1. Department of Cardiopulmonary Bypass, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, P. R. China
- Publication Type:Journal Article
- Keywords:
Deep hypothermic circulatory arrest;
rat model;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2022;29(12):1678-1685
- CountryChina
- Language:Chinese
-
Abstract:
Deep hypothermic circulatory arrest (DHCA) technology is the basic means of organ protection in complex aortic arch surgeries, congenital heart disease surgeries, pulmonary endarterectomy and other operations. The establishment of DHCA in rat model is helpful to explore the influence of DHCA and its pathophysiological pathways. However, there are some problems in this process, such as imperfect monitoring, inaccurate management and non-standard heparinization during the experimental period. It is necessary to review relevant literatures on DHCA rat model, in order to establish a DHCA rat model with standardized operation, clear standards and mature technology.
