Clinical research progress on brain natriuretic peptide and amino-terminal pro-brain natriuretic peptide
- VernacularTitle:脑钠肽与氨基末端脑钠肽前体临床研究进展
- Author:
Yihao ZHU
1
;
Fei WANG
1
;
Tao ZHU
1
Author Information
1. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China
- Publication Type:Journal Article
- Keywords:
Brain natriuretic peptide;
amino-terminal pro-brain natriuretic peptide;
heart failure;
resarch progress;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2022;29(12):1665-1670
- CountryChina
- Language:Chinese
-
Abstract:
Brain natriuretic peptide (BNP) and amino-terminal pro-brain natriuretic peptide (NT-proBNP) were the main members of the natriuretic peptide family. BNP has the effects of diuretic sodium, reducing sympathetic nervous system activity, dilating blood vessels, and improving the pathological remodeling of heart. Plasma BNP/NT-proBNP levels have been widely used in the diagnosis, severity assessment, prognosis prediction and treatment guidance of heart failure. In recent years, BNP/NT-proBNP has become a research hotspot in the diagnosis and and prognosis judgment of atrial fibrillation, recurrence of atrial fibrillation after radiofrequency ablation and cardioversion and congenital heart disease in infants and children, prediction of postoperative complications, and drug development. This article reviews the latest advances in clinical application and research progress on BNP/NT-proBNP.
