Cytotoxicity of oleanane type triterpene from leaf extract of Pterospermum acerifolium (in vitro) and theoretical investigation of inhibitory signaling pathway
10.1016/j.chmed.2020.09.004
- Author:
Mohd REHAN
1
;
Mohd SHAFIULLAH
1
;
Mohd SULTANAT
1
Author Information
1. Department of Chemistry, Aligarh Muslim University
- Publication Type:Journal Article
- Keywords:
breast cancer;
MDA-MB-231;
mTOR;
PI3K;
Pterospermum acerifolium (L.) Willd
- From:
Chinese Herbal Medicines
2021;13(1):124-130
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the cytotoxic activity of taraxerol isolated from the leaves of Pterospermum acerifolium and its EtOH extract against human breast, colon, and lung cancer cell lines and docking studies. Methods: The structures of the isolated compounds were elucidated by several spectroscopic methods such as
