Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer
10.1016/j.chmed.2021.10.008
- Author:
Xinnan LIU
1
;
Jingze ZHANG
1
;
Dailin LIU
1
;
Xinnan LIU
2
;
Shuping WANG
3
;
Jingyang LI
4
Author Information
1. Tianjin Modern Innovation Chinese Medicine Technology Co., Ltd.
2. Tianjin University of Traditional Chinese Medicine
3. Department of Pharmacy, Tianjin Provincial Corps Hospital, Chinese People's Armed Police Forces
4. Logistics College of Chinese People's Armed Police Forces
- Publication Type:Journal Article
- Keywords:
chronic atrophic gastritis;
gastric cancer;
signaling pathway;
traditional Chinese medicines
- From:
Chinese Herbal Medicines
2022;14(1):5-19
- CountryChina
- Language:Chinese
-
Abstract:
Chronic atrophic gastritis (CAG), a common disease of digestive system, is an extremely important cause of gastric cancer (GC). The occurrence and development of CAG involves the abnormality of multiple signaling pathways. Traditional Chinese medicines (TCMs) has the advantages of mild action, multi-target and small adverse reaction, etc., which broadens the way for the treatment of the disease, and TCMs can play a therapeutic role by regulating multiple signaling pathways. In this review, based on the related experiments of TCMs and Chinese herbal compounds in recent years, the related literatures were searched and 10 kinds of signaling pathways involved were summarized, in order to provide a reference for further research on reversing or delaying the progress of CAG and preventing gastric cancer.
