Rapid quantitative analysis of 12 chemical constituents in wild-simulated and cultivated Astragali Radix based on UHPLC-MS
10.1016/j.chmed.2021.06.007
- Author:
Dan LI
1
;
Yuetao LIU
1
;
Xuemei QIN
1
;
Dan LI
2
;
Yuetao LIU
2
;
Xuemei QIN
2
Author Information
1. Modern Research Center for Traditional Chinese Medicine, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University
2. Shanxi Key Laboratory of Effective Substances Research and Utilization in Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Astragali Radix;
chemical constituent;
cultivation method;
quantification;
UHPLC-MS
- From:
Chinese Herbal Medicines
2022;14(3):464-469
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Astragali Radix (AR) is one of the most widely used traditional Chinese medicines (TCMs) for tonic, which can be divided into wild-simulated and cultivated AR according to its cultivation method. However, whether cultivated AR can replace wild-simulated AR has always been a concern. Methods: In this study, a rapid, highly sensitive and specific analytical method using ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS) was developed to quantitatively measure 12 chemical constituents of AR in the different cultivation methods. Results: AR samples were analyzed with a good linear regression relationship (R
