Study on Event-Related Potential N400 for Chinese Aphasia Patients

VernacularTitle:汉语失语症患者的N400 研究
Author: Liang ZHOU ; Xiangming YE ; Juebao LI ; Wanshun WEN
Publication Type:Journal Article
Keywords: Chinese, aphasia, event-related potential, N400
From: Chinese Journal of Rehabilitation Theory and Practice 2012;18(8):710-712
CountryChina
Language:Chinese
Abstract: Objective To investigate the feature of event-related potential N400 for Chinese aphasia patients. Methods 23 Chinese aphasia patients and 20 controls were evaluated with Western Aphasia Battery (WAB), and N400 was also measured. Results N400 latency was longer and N400 amplitude was higher in the aphasia group than in the control group. In aphasia group, the latency (r=-0.553, P=0.000) and amplitude of N400 (r=-0.628, P=0.000) correlated to the score of Aphasia Quotient (AQ), and the amplitude of N400 correlated to the score of anomia in WAB (r=-0.372, P=0.001). Conclusion Event-related potential N400 could reflect the level of language function impairment and it is a valuable index for evaluating language function, especially anomia level in Chinese aphasia patients