Evaluation of reliability and validity of the Chinese version of a new symptom score of laryngopharyngeal reflux disease.
10.3760/cma.j.cn115330-20220531-00322
- VernacularTitle:反流症状评分量表中文版的信度和效度评估
- Author:
Hong Lei HAN
1
;
Qiu Ping LYU
1
;
Jian Feng LIU
1
;
Jian Hui ZHAO
1
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, China-Japan Friendship Hospital, Beijing 100029, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Laryngopharyngeal Reflux/diagnosis*;
Reproducibility of Results;
Retrospective Studies;
Quality of Life;
Proton Pump Inhibitors/therapeutic use*;
China
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2022;57(10):1185-1190
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To produce the Chinese version of a new reflux symptom score (RSS) of laryngopharyngeal reflux disease (LPRD) and to evaluate its reliability, validity and clinical value. Methods: This was a retrospective study which contained 42 healthy volunteers and 135 possible LPRD patients. RSI,RFS,oropharyngeal pH monitoring (Dx-pH monitoring) and RSS of each patient were performed. RSS was performed again after 1 week. Confirmed LPRD patients were treated with proton pump inhibitor for 8 week. And RSS was performed again after treatment. Reliability and validity of RSS were evaluated. Results: The Cronbach's α coefficient of RSS was 0.77, which indicated good internal reliability of the new score. The results of test-retest found all P values were less than 0.05, which supported good external reliability. Comparing RSS with laryngopharyngeal reflux test results, the diagnostic coincidence rate was 84.44% (114/135), and the positive predictive value was 85.71% (114/133), which showed good criterion validity. After 8 weeks treatment of PPI, RSS decreased significantly (pretreatment 84.79±42.50,posttreatment 20.11±22.82,t=-10.54, P<0.001), indicating good reactivity of RSS. The score of quality of life impact (Qol) in possible LPRD patients was obviously higher than that of healthy volunteers (t=7.15,P<0.001). All patients and volunteers believed that RSS was a good way to evaluate their symptoms. Conclusions: The new score RSS have good internal and external reliability, criterion validity and reactivity. RSS can be one of the important reference indexes to evaluate LPRD.
