Development of bariatric surgery in the context of precision medicine.
10.3760/cma.j.cn441530-20220630-00286
- Author:
Li Na GUO
1
;
Ke Yu YANG
1
;
Yong WANG
1
Author Information
1. Department of 4th General Surgery, the Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China.
- Publication Type:Journal Article
- MeSH:
Bariatric Surgery/methods*;
Epigenesis, Genetic;
Humans;
Precision Medicine
- From:
Chinese Journal of Gastrointestinal Surgery
2022;25(10):928-936
- CountryChina
- Language:Chinese
-
Abstract:
Precision medicine, which is based on individualized medicine, is a new medical model developed with the cross-application of genome sequencing technology, bioinformatics, and big data science. The establishment of precision medicine model is conducive to maximize the efficient utilization of medical resources and patient benefits. Bariatric surgery is an emerging branch of general surgery in the new century. Although the development of bariatric surgery still has a long way to go, precision medicine will add significant value to the rapid and positive development of the branch of bariatric surgery. In the context of precision medicine, bariatric metabolic surgery is now in its infancy. Currently, the successful implementation of precision control in bariatric surgery is initially focusing on the prediction of postoperative weight and the study of body weight differences in epigenetics. However, there are still gaps to be filled in the area of postoperative recovery, nutritional support treatment, and realization of individualized treatment based on big data. In the future, the integration of large-scale resource and data information can be realized by establishing the multi-center clinical sample library and perfecting the data collection of long-term follow-up and clinical information. Meanwhile, we can conduct deep biological data mining effectively with the big data platform, while using data reference to achieve accurate prediction and control of obesity treatment, so as to formulate detailed implementation plans and detailed procedure standard. Last but not least, we should pay attention to the patients' privacy and prevent personal health information leakage.
