Gut microbiota and immune-related diseases.
10.3760/cma.j.cn441530-20211130-00480
- Author:
Zhong Yuan WANG
1
;
Jian Feng GONG
1
Author Information
1. Department of General Surgery, Jinling Hospital, Nanjing 210002, China.
- Publication Type:Journal Article
- MeSH:
Gastrointestinal Microbiome/physiology*;
Humans;
Inflammatory Bowel Diseases;
Intestines
- From:
Chinese Journal of Gastrointestinal Surgery
2022;25(9):777-783
- CountryChina
- Language:Chinese
-
Abstract:
There are direct and indirect interactions between gut microbiota and host immune response, which can have a multifaceted impact on host health. Dysbiosis caused by disturbances in the gut microbiota is associated with susceptibility to many diseases, especially immune-related diseases. Based on the research results in recent years, this paper introduced the mechanism of the interaction between gut microbiota and host immunity, and expounded the role of gut microbiota in the occurrence and development of immune-related diseases, including intestinal system diseases such as inflammatory bowel disease and other systemic diseases such as rheumatoid arthritis, and summarized disease treatment strategies targeting gut microbiota. A better understanding of the research progress of gut microbiota and immune-related diseases will help us in the prevention and management of such diseases, and broaden our path to discover disease intervention targets.
