Research progress of the application of methacrylic anhydride gelatin hydrogel in wound repair.
10.3760/cma.j.cn501225-20220308-00056
- VernacularTitle:甲基丙烯酸酐化明胶水凝胶在创面修复领域中的应用研究进展
- Author:
Neng DING
1
;
Xin Xin FU
2
;
Hai Mei WU
3
;
Lie ZHU
1
Author Information
1. Department of Burn & Plastic Surgery, the Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China.
2. School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.
3. School of Health Sciences and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Gelatin/chemistry*;
Hydrogels;
Anhydrides;
Quality of Life;
Methacrylates/chemistry*
- From:
Chinese Journal of Burns
2022;38(11):1096-1100
- CountryChina
- Language:Chinese
-
Abstract:
Wound repair is a common clinical problem, which seriously affects the quality of life of patients and also brings a heavy burden to the society. Hydrogel-based multifunctional dressing has shown strong potential in the treatment of acute and chronic wounds. In addition to its good histocompatibility, cell adhesion, and biodegradability, methacrylic anhydride gelatin (GelMA) hydrogel has also attracted much attention due to its low cost, mild reaction conditions, adjustable physicochemical properties, and wide clinical applications. In this paper, the characteristics of GelMA hydrogel and its research progress in wound repair are introduced, and the future development of multifunctional GelMA hydrogel dressing for wound treatment is prospected.
