To strengthen the basic and translational research of mesenchymal stem cell-based therapy for refractory wounds.
10.3760/cma.j.cn501225-20220913-00405
- VernacularTitle:加强难愈合创面间充质干细胞治疗的基础与转化研究
- Author:
Chun Meng SHI
1
Author Information
1. Institute of Rocket Force Medicine, State Key Laboratory of Trauma, Burns and Combined Injury, Army Medical University, Chongqing 400038, China.
- Publication Type:Journal Article
- MeSH:
Translational Research, Biomedical;
Mesenchymal Stem Cells/metabolism*;
Stem Cell Transplantation;
Wound Healing
- From:
Chinese Journal of Burns
2022;38(11):999-1003
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the application of cell-based therapy in the field of refractory wound repair has shown broad prospects, among which the mesenchymal stem cell is the most concerned and widely studied cell type. Despite the rapid development of clinical translational research, the therapeutic effect of cell-based therapy is not consistent, and most clinical trials have not achieved the desired results. Further studies have found that heterogeneity is an important issue that restricts the further development of cell-based therapy and urgently needs to be studied. Based on the research progress of mesenchymal stem cells, in the review, we discuss the current status and challenges of cell-based therapy strategies for refractory wounds.
