Research advances on the construction of artificial dermal scaffolds based on biomaterials.
10.3760/cma.j.cn501225-20220606-00221
- Author:
Ji Qiu CHEN
1
;
Shi Hui ZHU
1
Author Information
1. Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Burn Institute of PLA, Shanghai 200433, China.
- Publication Type:Journal Article
- MeSH:
Biocompatible Materials/chemistry*;
Tissue Scaffolds/chemistry*;
Skin, Artificial;
Skin;
Polymers/chemistry*;
Cytokines
- From:
Chinese Journal of Burns
2022;38(10):968-972
- CountryChina
- Language:Chinese
-
Abstract:
In the field of wound repair, scarless healing and complete reconstruction of skin function are major challenges in clinical and basic research. At present, a variety of artificial dermal scaffolds have been used in the clinical repair of wounds to overcome the problems such as skin structural disorders caused by tissue defects. The biomaterials used to make artificial dermal scaffolds in skin and tissue engineering research mainly include three categories: natural biomaterials, biosynthetic materials, and organic polymer materials. This review summarizes the biocompatibility, bioactivity, and degradability of biomaterials and their effects on wound healing, and provides an overview of artificial dermal scaffold construction strategies based on biomaterials, wound healing cells, and associated cytokines.
