Research advances on the regulatory mechanism of sweat secretion ion channels of eccrine sweat glands.
10.3760/cma.j.cn501120-20210517-00191
- Author:
Jia Sheng SHEN
1
;
Yong An XU
2
Author Information
1. Department of Emergency, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu 322014, China.
2. Department of Emergency, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
- Publication Type:Review
- MeSH:
Eccrine Glands/metabolism*;
Humans;
Sweat/metabolism*
- From:
Chinese Journal of Burns
2022;38(8):794-798
- CountryChina
- Language:Chinese
-
Abstract:
Sweat glands are widely distributed in human skin, among which eccrine sweat glands play major roles in heat dissipation and sweat secretion. Sweat secretion is mainly regulated by nervous system and includes two processes of secretion of secretory coil and reabsorption of sweat duct, involving various ion channels and proteins such as calcium ion channel, potassium ion channel, sodium-potassium-chloride co-transporter 1, Best2 protein, aquaporin 5, cystic fibrosis transmembrane conductance regulator, and epithelial sodium ion channel. This paper reviews the nerve conduction system and various ion channels involved in sweat secretion of exocrine sweat glands in order to provide a theoretical basis for the study of regeneration, repair, and transformation of stem cells.
