Hepatocellular carcinoma immune microenvironment.
10.3760/cma.j.cn501113-20220703-00365
- Author:
Tong Guo MIAO
1
;
Yue Min NAN
1
Author Information
1. Third Hospital of Hebei Medical University, Shijiazhuang 050051, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Carcinoma, Hepatocellular/pathology*;
Liver Neoplasms/pathology*;
Tumor Microenvironment;
Immunotherapy
- From:
Chinese Journal of Hepatology
2022;30(9):923-930
- CountryChina
- Language:Chinese
-
Abstract:
The tumor immune microenvironment (TIME) plays crucial roles in the growth, progression, and therapeutic response of hepatocellular carcinoma(HCC) which is a prototypical inflammation-associated cancer. The efficacy of immunotherapy largely depends on the TIME. Targeting the immune microenvironment is an attractive strategy for the treatment of HCC. This review provides the characteristics of immune microenvironment of HCC,therapeutic approaches based on immune microenvironment,and information on the immune microenvironment underlying the response or resistance of HCC to immunotherapies.
