Research progress in association between endothelial dysfunction and periodontitis.
10.3760/cma.j.cn112144-20220216-00064
- Author:
Shu Rong YANG
1
;
Xiu Yun REN
1
Author Information
1. Department of Periodontology, Shanxi Medical University School and Hospital of Stomatology & Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Taiyuan 030001, China.
- Publication Type:Journal Article
- MeSH:
Cardiovascular Diseases/etiology*;
Endothelium, Vascular;
Humans;
Oxidative Stress;
Periodontitis/complications*;
Risk Factors
- From:
Chinese Journal of Stomatology
2022;57(9):973-977
- CountryChina
- Language:Chinese
-
Abstract:
Vascular endothelium formulates the basic defense against cardiovascular diseases. Multiple factors such as inflammatory factors, oxidative stress and biological factors can cause endothelial dysfunction and be involved in the formation and development of cardiovascular diseases. In studies of recent years, accumulated evidences showed that periodontitis was an independent risk factor for cardiovascular events, and was related to vascular endothelial dysfunction. Periodontal therapy could improve the vascular endothelial function. In this paper, the epidemiological evidences of associations between periodontitis and vascular endothelial dysfunction in recent years were listed, and the possible mechanisms of periodontitis aggravating endothelial dysfunction were analyzed. The importance of periodontal intervention in improving endothelial function was emphasized. This will provide new ideas for further study about the relationship between periodontitis and cardiovascular diseases and for the prevention and treatment strategies.
