The research progress of metabolism and occupational biological exposure index metabolism of inorganic arsenic and its compounds.
10.3760/cma.j.cn121094-20211231-00647
- Author:
Xin CHOU
1
;
Zhen MIN
1
Author Information
1. Poisoning department of Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai 200433, China.
- Publication Type:Journal Article
- Keywords:
Biological exposure index;
Inorganic arsenic;
Methylation;
Occupational exposure
- MeSH:
Arsenicals;
Arsenic;
Occupational Exposure;
Drinking Water;
Liver/metabolism*
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(11):876-880
- CountryChina
- Language:Chinese
-
Abstract:
Arsenic is a common metal-like element. Drinking arsenic-containing water and occupational exposure to arsenic are the main ways exposure to arsenic for population. Long-term exposure to arsenic can cause various organs dysfunction and cancer. After entering the body, inorganic arsenic is mainly methylated into monomethyl arsenic and dimethyl arsenic in the liver. Only a small part of inorganic arsenic is metabolized in the kidneys and lungs, and finally the metabolites of arsenic are excreted in the urine. understanding the biological characteristics of arsenic absorption, metabolism, and distribution in the body and formulating biological indicators related to occupational exposure to arsenic and can provide a scientific basis for the prevention and treatment of arsenic-related diseases. This article will review the biological monitoring indicators of occupational exposure to arsenic and the metabolic process of arsenic in the body.
