A report of 7 cases of toxic liver disease caused by mixed gas in a shoe factory.
10.3760/cma.j.cn121094-20220120-00036
- Author:
Yan Mei SHENG
1
;
Jian Hua XIAO
1
Author Information
1. Huizhou Institute for the Prevention and Treatment of Occupational Diseases, Huizhou 516008, China.
- Publication Type:Journal Article
- Keywords:
Dichloromethane;
Gas Poisoning;
Liver Diseases;
Mixed gases;
Shoe factory;
Toxic liver disease;
Trichloromethane
- MeSH:
Humans;
Alanine Transaminase;
Aspartate Aminotransferases;
Gas Poisoning;
Liver Diseases
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(11):854-856
- CountryChina
- Language:Chinese
-
Abstract:
Trichloromethane and dichloromethane have toxic effects on the liver, and incidents of toxic liver disease caused by them have been reported from time to time. In November 2021, an occupational chemical poisoning incident occurred in a shoe factory in Huidong County, Guangdong Province. After testing the air at the scene and analyzing the clinical data of the poisoning patients, it was preliminarily determined that the poisoning was caused by a mixed gas poisoning incident dominated by trichoromethane. At admission, the liver function of 7 patients was tested for different degrees of impairment (alanine aminotransferase 145-2501 IU/L, aspartate aminotransferase 66-1286 IU/L). The volatile organic components of on-site raw and auxiliary materials were analyzed. The percentages of trichloromethane and dichloromethane detected in 103A powder glue used in the poisoning workshop site accounted for 21.11% and 6.77% respectively.
