Research progress of occupational and environmental exposure and idiopathic pulmonary fibrosis.
10.3760/cma.j.cn121094-20210309-00132
- Author:
Zi Yun GUO
1
;
Qiao YE
1
Author Information
1. Department of Occupational Medicine and Toxicology, Clinical Center for Interstitial Lung Diseases, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
- Publication Type:Journal Article
- Keywords:
Dust;
Environment;
Exposure;
Idiopathic;
Occupation;
Pulmonary fibrosis
- MeSH:
Humans;
Idiopathic Pulmonary Fibrosis/etiology*;
Dust;
Environmental Exposure/adverse effects*;
Occupational Exposure/adverse effects*;
Lung Diseases, Interstitial
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(10):790-794
- CountryChina
- Language:Chinese
-
Abstract:
Occupational and environmental exposure can directly cause specific lung diseases, and can also induce autoimmune diseases that can lead to various types of interstitial lung diseases. In recent years, it was discovered that certain occupational and environmental exposure was related to the increased risk of Idiopathic pulmonary fibrosis (IPF) disease and progression, including metal and mineral dust, wood dust, organic dust, asbestos dust, silica dust, cigarette smoke and air pollution. IPF is a chronic progressive fibrotic lung disease of unknown etiology, with a characteristic imaging and histologic pattern called usual interstitial pneumonia. This article is a review based on the correlation and mechanism of occupational and environmental exposure in the pathogenesis and disease progression of IPF to improve the understanding of the disease and promote the formulation of treatment plans.