One case of rhabdomyolysis caused by acute phoxim poisoning.
10.3760/cma.j.cn121094-20211027-00520
- Author:
Jia Ning WANG
1
;
Che WANG
1
;
Jun WANG
1
;
Yong Xin SONG
1
;
Ya Ping HE
1
;
Zhao Xin LU
1
Author Information
1. Emergency Department, Qingdao Hospital of Traditional Chinese Medicine (Qingdao Hiser Hospital) , Qingdao 266033, China.
- Publication Type:Journal Article
- Keywords:
Blood purification;
Organophosphate poisoning;
Phoxim;
Rhabdomyolysis
- MeSH:
Humans;
Rhabdomyolysis/chemically induced*;
Organothiophosphorus Compounds;
Creatine Kinase;
Incidence;
Acute Kidney Injury
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(10):782-784
- CountryChina
- Language:Chinese
-
Abstract:
Patients with organophosphate poisoning usually die from respiratory depression and respiratory failure. The incidence of rhabdomyolysis is relatively low, but the mortality rate is extremely high once it occurs. In this paper, the treatment of a patient with acute phoxim poisoning was analyzed. The patient developed severe rhabdomyolysis syndrome on the 3rd day of treatment, the creatine kinase exceeded the normal value by more than 300 times (up to 103510.65 U/L) , and renal failure occurred. Clinical treatment included active detoxification, blood purification, organ support, and internal environment maintenance. The patient's rhabdomyolysis continued, and the condition worsened. Finally, the family gave up the treatment and the patient died. It is suggested that attention should be paid to the occurrence of rhabdomyolysis syndrome during the treatment of organophosphorus poisoning, and timely blood purification technology may be the key to treatment.
