A case of bromadiolone poisoning leading to digestive tract, abdominal hemorrhage and secondary paralytic ileus.
10.3760/cma.j.cn121094-20210617-00295
- Author:
Hong Fan CHEN
1
;
Zhi Jian ZHANG
2
;
Cheng Jin YOU
1
;
Li CHEN
1
Author Information
1. Emergency Department of Banan District People's Hospital of Chongqing, Chongqing 401320, China.
2. Emergency Department of Banan District People's Hospital of Chongqing, Chongqing 401320, China Critical Care Medicine of Banan District People's Hospital of Chongqing, Chongqing 401320, China.
- Publication Type:Journal Article
- Keywords:
Abdominal hemorrhage;
Bromadiolone;
Gastrointestinal bleeding;
Imaging manifestations;
Paralytic ileus;
Poisoning
- MeSH:
4-Hydroxycoumarins;
Blood Coagulation Factors;
Dicumarol;
Hemorrhage;
Humans;
Intestinal Pseudo-Obstruction/chemically induced*;
Oxidoreductases;
Rodenticides;
Vitamin K 1;
Warfarin
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(9):707-709
- CountryChina
- Language:Chinese
-
Abstract:
Bromadiolone, commonly known as super warfarin, is a long-acting coumarin dicoumarin rodenticide. The mechanism of bromadiolone is mainly to inhibit vitamin K1 epoxide reductase and affect the synthesis of coagulation factors Ⅱ, Ⅶ, Ⅸ and Ⅹ, which causes blood coagulation dysfunction and systemic multiple organ hemorrhage. Here, we report of a case of bromadiolone poisoning patient who had digestive tract, abdominal hemorrhage, as well as secondary paralytic ileus. After blood product transfusion and vitamin K1 supplementation, the patient was discharged after the physical condition was improved. It's suggestied that clinicians should pay attention to rare complications to prevent missed diagnosis when treating other bromadiolone poisoning.
