Analysis of current status and influencing factors of inflammatory factors among electrical workers in Hainan province.
10.3760/cma.j.cn121094-20211130-00588
- VernacularTitle:海南省电力工人炎症因子水平及影响因素分析
- Author:
Jin Ke HAN
1
;
Bin LI
2
;
Chan Juan ZHAO
1
;
Shan He LIU
1
;
Hui Yu TANG
1
;
Zhen YAN
1
Author Information
1. School of Public Health, Hainan Medical University, Haikou 571199, China.
2. Hainan Center for Disease Control and Prevention, Haikou 570203, China.
- Publication Type:Journal Article
- Keywords:
Chemokines;
Electrical worker;
Inflammatory factors;
Influencing factors;
Interleukin;
Tumor Necrosis Factor;
Worker
- MeSH:
Adult;
Female;
Humans;
Interleukin-6/blood*;
Interleukin-8/blood*;
Male;
Middle Aged;
Occupational Exposure;
Surveys and Questionnaires;
Tumor Necrosis Factor-alpha/blood*;
Young Adult
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(8):586-591
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the level and influence factors of inflammatory factors among electrical workers in Hainan Province. Methods: A total of 509 electrical workers were selected as the research subjects with random cluster sampling in September 2020. Basic information was collected by questionnaire, the serum IL-6, IL-8 and TNF-α levels of the subjects were detected by Luminex.Mann-Whitney U test and Kruskal-wallis H test were used for univariate analysis. Ordinal logistic regression analysis was used for potential influencing factors of the level of inflammatory factors. Results: The median concentrations of IL-6, IL-8 and TNF-α in serum were 2.78, 9.77 and 8.18 pg/ml. Compared with women, male was a risk factor for the increase of IL-6 levels (OR=1.80, 95%CI: 1.08~3.00, P=0.024) . Compared with 51-60 years old, 21-31 years old (OR=0.27, 95%CI: 0.18~0.42, P<0.001) , 31-41 years old (OR=0.27, 95%CI: 0.17~0.43, P<0.001) and 41-51 years old (OR=0.64, 95%CI: 0.41~0.99, P=0.043) were protective factors for the increase of IL-8 level. Compared with day shift workers, shift work was a risk factor for the increase of IL-8 level (OR=1.73, 95%CI: 1.21~2.48, P=0.003) . Compared with women, male was a risk factor for the increase of TNF-α levels (OR=2.87, 95%CI: 1.70~4.86, P<0.001) . Compared with workers who exposed to 7 or more occupational hazard factors, exposed to 1~3 (OR=0.53, 95%CI: 0.30~0.92, P=0.024) occupational hazard factors were protective factors for the increase of TNF-α levels. Conclusion: The level of inflammatory factors was related to sex, age, work system and occupational environment, which can provide basic data for follow-up research on occupational population.
