Consideration of diagnosing extremely well differentiated adenocarcinoma of gastrointestinal tract.
10.3760/cma.j.cn112151-20220517-00425
- Author:
Wei Xun ZHOU
1
;
Jie CHEN
1
Author Information
1. Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
- Publication Type:Journal Article
- MeSH:
Adenocarcinoma/pathology*;
Gastrointestinal Tract/pathology*;
Humans
- From:
Chinese Journal of Pathology
2022;51(8):693-695
- CountryChina
- Language:Chinese
-
Abstract:
For gastrointestinal adenocarcinoma with excellent differentiation, some diagnostic names have emerged in recent years, which have overlapping and different meanings. Low-grade well differentiated adenocarcinoma and very well differentiated adenocarcinoma are terms for a group of adenocarcinomas with good differentiation and little cellular atypia, including a variety of histological types. It is suggested that specific histological types should be listed as far as possible in diagnosis, instead of using "low-grade well differentiated adenocarcinoma" or "very well differentiated adenocarcinoma" as a complete diagnosis. This kind of adenocarcinomas may lack cellular pleomorphism, so it is necessary to observe the structural atypia for diagnosis. At the same time, attention should be paid to the differentiation of reactive changes, low grade dysplasia, epithelial misplacement and other lesions.
