Multiple intracranial aneurysms associated with branchio-oto-dysplasia.
10.3346/jkms.2001.16.2.245
- Author:
Jin Hwan CHEONG
1
;
Choong Hyun KIM
;
Koang Hum BAK
;
Jae Min KIM
;
Suck Jun OH
Author Information
1. Department of Neurosurgery, Hanyang University Kuri Hospital, Hanyang University College of Medicine, Kuri, Korea. KCH5142@email.hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Branchio-Oto-Renal Syndrome;
Intracranial Aneurysm;
Subarachnoid Hemorrhage
- MeSH:
Adult;
Branchio-Oto-Renal Syndrome/*complications;
Cerebral Angiography;
Human;
Intracranial Aneurysm/*etiology/radiography;
Subarachnoid Hemorrhage/etiology/radiography;
Temporal Bone/abnormalities;
Tomography, X-Ray Computed;
Zygoma/abnormalities
- From:Journal of Korean Medical Science
2001;16(2):245-249
- CountryRepublic of Korea
- Language:English
-
Abstract:
Branchio-oto-dysplasia is characterized by abnormalities of embryonic branchial arch system and deafness inherited as autosomal dominant with variable gene expression. We present a rare case of multiple intracranial aneurysms associated with branchio-oto-dysplasia. A 40-yr-old man with severe headache presented as spontaneous subarachnoid hemorrhage on brain computed tomographic scan. The patient also manifested clinical features of branchio-oto-dysplasia and right hemifacial hypoplasia. Carotid angiogram confirmed an aneurysm in the anterior communicating artery. Intraoperative findings demonstrated multiple aneurysms in the anterior communicating artery and in the left posterior communicating artery, which were clipped successfully. Postoperative course was uneventful. This condition has not been reported previously. We also reviewed literatures to discuss whether the intracranial aneurysm was as a coincidental finding or a part of this malformation.
