Association between body mass index and coronary heart disease in Qingdao: a prospective study.
10.3760/cma.j.cn112338-20211012-00789
- Author:
Jia Hui SONG
1
;
Chi PAN
1
;
Fei Fei LI
2
;
Xiao Jia XUE
2
;
Yu GUO
3
;
Pei PEI
3
;
Xiao Cao TIAN
4
;
Shao Jie WANG
2
;
Ru Qin GAO
5
;
Zeng Chang PANG
2
;
Zhengming CHEN
6
;
Liming LI
7
Author Information
1. Department of Nutrition and Food Hygiene, School of Public Health, Qingdao University, Qingdao 266071, China.
2. Department of Non-communicable Disease Control and Prevention, Qingdao Prefectural Center for Disease Control and Prevention, Qingdao 266033, China.
3. Chinese Academy of Medical Sciences, Beijing 100730, China.
4. Department of Non-communicable Disease Control and Prevention, Qingdao Prefectural Center for Disease Control and Prevention, Qingdao 266033, China Qingdao Institute of Preventive Medicine, Qingdao 266033, China.
5. Department of Nutrition and Food Hygiene, School of Public Health, Qingdao University, Qingdao 266071, China Qingdao Prefectural Center for Disease Control and Prevention, Qingdao 266033, China.
6. Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.
7. School of Public Health, Peking University, Beijng 100191, China Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing 100191, China.
- Publication Type:Journal Article
- MeSH:
Body Mass Index;
Coronary Disease/epidemiology*;
Humans;
Myocardial Ischemia/epidemiology*;
Obesity/epidemiology*;
Overweight/epidemiology*;
Prospective Studies
- From:Chinese Journal of Epidemiology
2022;43(9):1357-1363
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the association between body mass index (BMI) and coronary heart disease. Methods: The data for the present study were from the prospective cohort study of China Kadoorie Biobank (CKB) in Qingdao, a total of 33 355 participants aged 30-79 years were included in the study. Cox regression analyses were performed to evaluate the association between BMI and coronary heart disease. Results: During the follow-up for an average 9.2 years, a total of 2 712 cases of ischemic heart disease (IHD) and 420 cases of major coronary events (MCE) were found. Multivariate Cox regression analysis showed that, compared with participants with normal BMI, the participants who were overweight had a 41% and 87% higher risk of IHD and MCE, the adjusted HR were 1.41 (95%CI: 1.27-1.56) and 1.87 (95%CI: 1.43-2.44), respectively. The participants who were obesity had 91% and 143% higher risk of IHD and MCE, the adjusted HR were 1.91 (95%CI: 1.72-2.13) and 2.43 (95%CI: 1.82-3.24), respectively. Conclusion: Overweight and obesity might increase the risk for IHD and MCE.
