Serotyping methods of Streptococcus pneumonia.
10.3760/cma.j.cn112150-20220530-00543
- VernacularTitle:肺炎链球菌血清分型技术研究进展
- Author:
Jie CHE
1
;
Zhu Jun SHAO
1
Author Information
1. State Key Laboratory for Communicable Disease Prevention and Control, Department of Respiratory Infectious Diseases, Institute for Communicable Disease Prevention and Control, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Serotyping/methods*;
Pneumococcal Infections/prevention & control*;
Pneumococcal Vaccines;
Streptococcus pneumoniae/genetics*;
Pneumonia
- From:
Chinese Journal of Preventive Medicine
2022;56(10):1487-1493
- CountryChina
- Language:Chinese
-
Abstract:
More than 100 serotypes of Streptococcus pneumonia have been identified, which has been one bottleneck problem for pneumococcal disease diagnosis, surveillance, development of pneumococcal vaccine and effectiveness evaluation of pneumococcal vaccines. Three categories of approaches for pneumococcal serotyping will be discussed including phenotyping based on anti-serum, biochemical typing based on pneumococcal capsular characteristics and genotyping based on pneumococcal capsular locus sequences. We reviewed the development and applications of different serotyping of pneumococcus to provide guidance for pneumococcal disease prevention and control.
