Progress on the diagnosis and therapy about atopic diseases and primary immunodeficiency diseases.
10.3760/cma.j.cn112150-20220523-00518
- Author:
Zhou Xian PAN
1
;
Ying Yang XU
1
;
Sai Nan BIAN
1
;
Ji LI
2
;
Yu Lin JIANG
3
;
Ji LI
4
;
Kai GUAN
1
Author Information
1. Department of Allergy, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, Beijing 100730, China.
2. Department of Pediatrics, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
3. Department of Gynaecology and Obstetrics, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
4. Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
- Publication Type:Journal Article
- MeSH:
Autoimmune Diseases;
Child;
Humans;
Hypersensitivity/therapy*;
Immunologic Deficiency Syndromes/therapy*;
Primary Immunodeficiency Diseases/therapy*
- From:
Chinese Journal of Preventive Medicine
2022;56(9):1218-1225
- CountryChina
- Language:Chinese
-
Abstract:
Primary immunodeficiency diseases (PID) is a congenital disease caused by single gene germline mutation related to the immune system. PID patients have immune dysregulation, and are susceptible to infectious diseases, autoimmune diseases, autoimmune diseases, allergic diseases, and malignant tumors. The first symptom of some PID patients is atopic disease, therefore they go to the department of allergy, department of pediatrics and other relevant departments. How to identify and diagnose PID in allergic patients, to reduce diagnosis delay and prevent disease aggravation are the abilities that allergists, pediatricians, and doctors in other relevant departments need to master. This article summarizes the warning signs of PID in allergic patients and the mechanism of allergy combined with PID, and then summarizes the common types of PID in allergic patients, the evaluation, treatment and prevention in patients with PID and allergy.
