The role of gut microbiota dysbiosis in the occurrence and development of inflammatory bowel disease and its prevention and control strategies.
10.3760/cma.j.cn112150-20211008-00936
- VernacularTitle:肠道菌群失调在炎症性肠病发生发展中的作用及防控策略
- Author:
Zi Yu YANG
1
;
Min LI
1
Author Information
1. Department of Laboratory Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
- Publication Type:Journal Article
- MeSH:
Dysbiosis/therapy*;
Gastrointestinal Microbiome;
Humans;
Inflammatory Bowel Diseases/prevention & control*;
Microbiota
- From:
Chinese Journal of Preventive Medicine
2022;56(9):1175-1181
- CountryChina
- Language:Chinese
-
Abstract:
The occurrence of inflammatory bowel disease (IBD) is related to environmental factors, host immune status, genetic susceptibility and flora imbalance. With the development of sequencing technologies, the relationship between intestinal microbiota and IBD has been further studied and confirmed in many aspects. This article summarizes the characteristics of microbiota alterations in patients with IBD, as well as the role and mechanisms of microbiota dysbiosis in the onset and development of IBD, and discusses the research status of therapies based on intestinal microbiota, prospecting the future of intestinal flora in the prevention, diagnosis, treatment and prognosis of IBD.
