Relationship between dynamic changes of psychological distress and quality of life in Chinese early breast cancer patients.
10.3760/cma.j.cn112152-20210412-00308
- VernacularTitle:中国早期乳腺癌患者心理痛苦程度动态变化与生活质量的关系
- Author:
Dan LYU
1
;
Bo LAN
1
;
Xiao Ying SUN
2
;
Min YANG
3
;
Li ZHANG
4
;
Fei MA
1
Author Information
1. Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
2. Department of Medical Oncology, Cancer Hospital of Huanxing Chaoyang District, Beijing 100122, China.
3. Comprehensive Oncology Department, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
4. Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital &Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, China.
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Chemotherapy;
Psychological distress;
Quality of life
- MeSH:
Humans;
Female;
Quality of Life/psychology*;
Breast Neoplasms/psychology*;
Stress, Psychological/psychology*;
Prospective Studies;
Psychological Distress;
China;
Neoplasms;
Surveys and Questionnaires
- From:
Chinese Journal of Oncology
2022;44(10):1119-1124
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the dynamic changes of Distress Thermometer scores and the relationship between psychological distress and quality of life in Chinese early breast cancer patients during chemotherapy. Methods: This prospective study enrolled 110 Chinese postoperative early breast cancer patients between March 2019 and December 2019. The psychological distress and quality of life (QOL) of patients were assessed by using the psychological distress management screening tool and the patient quality of life scale. Logistic regression model was used to analyze the influencing factors of psychological distress degree. The correlation between distress thermometer (DT) score changes and quality of life was analyzed by Pearson correlation analysis. Results: In total, 96 valid cases were analyzed. Before chemotherapy, 47 cases (49.0%) had DT score ≥4 points. After 2 cycles of chemotherapy, 40 cases (41.7%) had DT score ≥4 points. Thirty-four patients (35.4%) had DT score ≥4 points after chemotherapy. The DT score after chemotherapy was lower than that before chemotherapy and after 2 cycles of chemotherapy. Univariate analysis showed that income level and pathological stage were still significant related to the detection of DT score ≥4 points after chemotherapy (P<0.05). The changes of DT scores before and after chemotherapy were negatively correlated with the changes of quality of life ( r=-0.298, P=0.003). Conclusions: The detection rate of psychological distress in patients with early breast cancer during chemotherapy showed a decreasing trend. Income level and tumor stage are significant factors affecting the psychological distress of patients. There is a significant correlation between the psychological distress and the quality of life during chemotherapy. We should pay attention to the evaluation and monitoring state of psychological distress of patients during chemotherapy.
