Regional disparities in trends of global gastric cancer incidence and mortality from 1990 to 2019.
10.3760/cma.j.cn112152-20220120-00049
- Author:
Dian Qin SUN
1
;
Fan YANG
1
;
He LI
1
;
Mao Mao CAO
1
;
Xin Xin YAN
1
;
Si Yi HE
1
;
Shao Li ZHANG
1
;
Chang Fa XIA
1
;
Wan Qing CHEN
1
Author Information
1. Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College/Chinese Academy of Medical Sciences Key Laboratory for National Cancer Big Data Analysis and Implement, Beijing 100021, China.
- Publication Type:Journal Article
- Keywords:
Epidemiology;
Gastric neoplasms;
Global burden of disease study;
Regional disparities
- MeSH:
Global Burden of Disease;
Global Health;
Humans;
Incidence;
Quality-Adjusted Life Years;
Stomach Neoplasms/epidemiology*
- From:
Chinese Journal of Oncology
2022;44(9):950-954
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To depict gastric cancer burden trends globally and analyze geographical and socioeconomic disparities among different countries and territories. Methods: We extracted the data from Global Burden of Disease 2019 Database. We conducted the Joinpoint regression and calculated the average annual percent change (AAPC) and corresponding 95% confidence interval (CI) for age-standardized gastric cancer incidence and mortality from 1990 to 2019. Linear regression was performed to measure the association of sociodemographic index (SDI) with each country's gastric cancer incidence and mortality AAPC. We applied the age-period-cohort analysis to assess the cohort effect on gastric cancer incidence and mortality. Results: The AAPCs for gastric cancer age-standardized incidence and mortality rates from 1990 to 2019 were -1.27% (95% CI: -1.43%, -1.11%) and -1.87% (95% CI: -2.01%, -1.72%), respectively. SDI levels were negatively associated with AAPCs, which means that countries with higher SDI had higher AAPC (P<0.001). The decrease of gastric cancer burden in countries with low or medium SDI levels was slower than that globally. The age-period-cohort analysis indicated that countries with higher SDI levels had more apparent decline in birth cohort effects from 1900 to 1999. Conclusions: Countries with different socioeconomic levels have various decreasing rates for gastric cancer incidence and deaths. Countries with higher SDI levels have higher declining rates for gastric cancer burden.
